Issue 1, 2011
From the journal:

Chemical Communications

Tools for metal ion sorting: in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms†‡

Oksana I. Leszczyszyn,a   Sukaina Zeitoun-Ghandour,b   Stephen R. Stürzenbaumb  and  Claudia A. Blindauer*a  

* Corresponding authors

a Department of Chemistry, University of Warwick, Coventry, UK
E-mail: c.blindauer@warwick.ac.uk
Tel: +44 (0)2476528264

b Division of Pharmaceutical Science, School of Biomedical and Health Sciences, King's College London, UK.

Abstract

In vitro evidence for the isoform-specific partitioning of cadmium and zinc ions between the two C. elegans metallothioneins is presented. This observation is discussed in terms of isoform-specific affinities towards zinc and cadmium and the implications of our study on the in vivo roles of C. elegans metallothioneins.

Graphical abstract: Tools for metal ion sorting: in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms

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Article information

DOI
https://doi.org/10.1039/C0CC02188A
Article type
Communication
Submitted
29 Jun 2010
Accepted
09 Sep 2010
First published
28 Sep 2010

Chem. Commun., 2011,47, 448-450

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Tools for metal ion sorting: in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms

O. I. Leszczyszyn, S. Zeitoun-Ghandour, S. R. Stürzenbaum and C. A. Blindauer, Chem. Commun., 2011, 47, 448 DOI: 10.1039/C0CC02188A

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