Issue 9, 2007
From the journal:

Green Chemistry

Eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones in ionic liquids or ionic liquid–water without additional catalyst†

Jiuxi Chen,b   Weike Su,*ab   Huayue Wu,*b   Miaochang Liub  and  Can Jina  

* Corresponding authors

a College of Pharmaceutical Sciences, Zhejiang University of Technology, Zhejiang Key Laboratory of Pharmaceutical Engineering, Hangzhou, P. R. China.
E-mail: suweike@zjut.edu.cn
Fax: +86 571 88320752

b College of Chemistry and Materials Science, Wenzhou University, Wenzhou, P. R. China.

Abstract

2,3-Dihydroquinazolin-4(1H)-ones have been synthesized in high to excellent yields through direct cyclocondensation of anthranilamides and aldehydes in ionic liquids (ILs) or one-pot three-component cyclocondensation of isatoic anhydrides, ammonium acetate and aldehydes in ionic liquid–water solvent system without the use of any additional catalyst.

Graphical abstract: Eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones in ionic liquids or ionic liquid–water without additional catalyst

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Article information

DOI
https://doi.org/10.1039/B700957G
Article type
Communication
Submitted
22 Jan 2007
Accepted
10 Apr 2007
First published
04 May 2007

Green Chem., 2007,9, 972-975

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Eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones in ionic liquids or ionic liquid–water without additional catalyst

J. Chen, W. Su, H. Wu, M. Liu and C. Jin, Green Chem., 2007, 9, 972 DOI: 10.1039/B700957G

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