Visible light induced hydroxyfluoroalkylation of quinoxalin-2(1H)-ones with N-trifluoroethoxyphthalimide under catalyst-free conditions

Abstract

For the first time, we achieved visible light-induced direct C3-hydroxyfluoroalkylation of quinoxalin-2(1H)-ones using N-trifluoroethoxyphthalimide as the trifluoroethanol radical precursor, without the need for a photocatalyst. The metal-free and catalyst-free nature of this method makes it an efficient and environmentally friendly approach for synthesizing C3-hydroxyfluoroalkylated quinoxalin-2(1H)-ones.