Plant-derived exosome-like nanoparticles in tissue repair and regeneration

Abstract

This article reviews plant-derived exosome-like nanoparticles (ELNs), and highlights their potential in regenerative medicine. Various extraction techniques, including ultracentrifugation and ultrafiltration, and their impact on ELN purity and yield were discussed. Characterization methods such as microscopy and particle analysis are found to play crucial roles in defining ELN properties. This review is focused on exploring the therapeutic potential of ELNs in tissue repair, immune regulation, and antioxidant activities. Further research and optimization methods for extraction of ELNs to realize clinical potential applications are necessary.

Graphical abstract: Plant-derived exosome-like nanoparticles in tissue repair and regeneration

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Article information

Article type
Review Article
Submitted
25 Oct 2024
Accepted
09 Dec 2024
First published
18 Dec 2024

J. Mater. Chem. B, 2025, Advance Article

Plant-derived exosome-like nanoparticles in tissue repair and regeneration

C. Gao, Y. Chen, X. Wen, R. Han, Y. Qin, S. Li, R. Tang, W. Zhou, J. Zhao, J. Sun, Z. Li, Z. Tan, D. Wang and C. Zhou, J. Mater. Chem. B, 2025, Advance Article , DOI: 10.1039/D4TB02394C

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