A Prussian blue-doped RGO/MXene composite aerogel with peroxidase-like activity for real-time monitoring of H2O2 secretion from living cells

Abstract

Herein, we develop a novel 3D composite aerogel (3D PB/GMA) and apply it to the real-time monitoring of H₂O₂ secretion from living cells. The 3D PB/GMA shows an obvious porous structure and superior peroxidase-like activity. The electrochemical sensor based on 3D PB/GMA shows an excellent electrocatalytic performance towards H₂O₂. When applied to the real-time tracking of H₂O₂ secretion from living cells, it can satisfactorily distinguish cancer cell lines from normal cell lines, revealing a good application potential in pathological diagnosis.