Issue 36, 2023

Organic room-temperature phosphorescence materials for bioimaging

Abstract

Organic room-temperature phosphorescence (RTP) materials are currently the focus of research in the field of bioimaging. In comparison with the conventional imaging modalities based on organic fluorescent dyes, RTP materials with long lifetime enable time-resolved imaging to improve the imaging resolution by avoiding autofluorescence. In this review, we will start with summarizing strategies for achieving high performance RTP materials for bioimaging, including the development of RTP-compounds, host–guest doping materials, and supramolecular assemblies. We then discuss the optimization of nanonization processes to obtain RTP nanoparticles with controllable size, high dispersibility, and improved stability. The differences between top-down and bottom-up approaches are further described. Finally, we briefly introduce the emerging methods for preparing RTP materials for bioimaging.

Graphical abstract: Organic room-temperature phosphorescence materials for bioimaging

Article information

Article type
Feature Article
Submitted
26 Feb 2023
Accepted
31 Mar 2023
First published
03 Apr 2023

Chem. Commun., 2023,59, 5329-5342

Organic room-temperature phosphorescence materials for bioimaging

Y. Zhang, H. Li, M. Yang, W. Dai, J. Shi, B. Tong, Z. Cai, Z. Wang, Y. Dong and X. Yu, Chem. Commun., 2023, 59, 5329 DOI: 10.1039/D3CC00923H

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