Issue 31, 2022
From the journal:

Chemical Communications

A dual-response NIR probe reveals positive correlation between biothiols and viscosity under cellular stress change†

Sha Li,a   Fangjun Huo, ORCID logo *b   Ying Wena  and  Caixia Yin ORCID logo *a  

* Corresponding authors

a Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China
E-mail: yincx@sxu.edu.cn

b Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China

Abstract

A mitochondrial targeted NIR fluorescent probe NIR-NBD was designed and developed for the detection of biothiols and viscosity. Furthermore, a positive correlation between the biothiol level and viscosity under cellular stress change was found for the first time, which provides some important correlation analysis information in the pathophysiological state.

Graphical abstract: A dual-response NIR probe reveals positive correlation between biothiols and viscosity under cellular stress change

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Article information

DOI
https://doi.org/10.1039/D2CC00668E
Article type
Communication
Submitted
14 Feb 2022
Accepted
17 Mar 2022
First published
23 Mar 2022

Chem. Commun., 2022,58, 4881-4884

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A dual-response NIR probe reveals positive correlation between biothiols and viscosity under cellular stress change

S. Li, F. Huo, Y. Wen and C. Yin, Chem. Commun., 2022, 58, 4881 DOI: 10.1039/D2CC00668E

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