Issue 6, 1997

Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side

Abstract

N-Fluorination and N-chlorination of methyl 2-trifluoromethylaziridine-2-carboxylate occurs predominantly from the more hindered side owing to the fixed orientation of the lone electron pair of the N atom caused by the formation of an intramolecular H-bond.

Article information

Article type
Paper

Mendeleev Commun., 1997,7, 229-230

Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side

V. V. Rozhkov, K. N. Makarov, S. N. Osipov, I. I. Chervin, A. V. Ignatenko and R. G. Kostyanovsky, Mendeleev Commun., 1997, 7, 229 DOI: 10.1070/MC1997v007n06ABEH000831

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