Issue 14, 1994

Design and synthesis of transition-state analogues for a cationic cyclisation

Abstract

Transition-state analogues based upon the 6-(hydroxymethyl)-13-azagona-1,3,5(10),8-tetraene structure (e.g., 40) have been designed and synthesized as part of a programme to elicit antibodies capable of catalysing cationic cyclisations. Methodology for conjugating such analogues to proteins has also been developed.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1994, 1997-2006

Design and synthesis of transition-state analogues for a cationic cyclisation

I. M. Bell, C. Abell and F. J. Leeper, J. Chem. Soc., Perkin Trans. 1, 1994, 1997 DOI: 10.1039/P19940001997

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