The chemistry of pseudomonic acid. Part 12. Preparation of diazole and triazole derivatives
Abstract
The preparations of examples of normonyl †; imidazoles, pyrazoles and triazoles are described. Most derivatives were formed by treatment of monic acid amides with triphenylphosphine based dehydrating agents, resulting in cyclisation or cycloaddition of the intermediate dipolar species. One example is the novel one pot reduction–cyclisation of an α-acylamino nitrite to an imidazole.