Issue 15, 1985

N-oxide as a potential function in the design of enzyme inhibitors. Application to 2,3-epoxysqualene-sterol cyclases

Abstract

The N-oxides of several tertiary amines possessing an aliphatic long chain are more potent inhibitors of 2,3-epoxysqualene-β-amyrin and -lanosterol cyclases than their parent amines.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1985, 1054-1055

N-oxide as a potential function in the design of enzyme inhibitors. Application to 2,3-epoxysqualene-sterol cyclases

M. Cerutti, L. Delprino, L. Cattel, P. Bouvier-Navé, A. Duriatti, F. Schuber and P. Benveniste, J. Chem. Soc., Chem. Commun., 1985, 1054 DOI: 10.1039/C39850001054

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements