Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum
Abstract
The structure of compactin (I){7-[1,2,6,7,8,8a-hexahydro-2-methyl-8-(2-methylbutyryloxy)naphthyl]-3-hydroxyheptan-5-olide}, a metabolite isolated from cultures of Penicillium brevicompactum, has been determined by a combination of spectroscopic, chemical, and X-ray crystallographic methods.