Kinetics and mechanism of trifluoroacetylation of aromatic compounds
Abstract
The trifluoroacetylation of 2-methylfuran in dichloroethane at 25° was found to obey third-order kinetics according to the equation v=KobsIII[substrate][anhydride][acid]. A mechanism involving the formation of an ion pair between the protonated anhydride and the trifluoroacetate anion as the acylating agent is suggested.