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Issue 55, 2020
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Furo[3,2-c]coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms

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Abstract

The isolation, biological activity and synthesis of natural furo[3,2-c]coumarins are presented, covering mainly the developments in the last 35 years. The most relevant approaches toward the synthesis of 2-substituted, 3-substituted and 2,3-disubstituted heterocycles are also discussed, with emphasis on the efficiency of the processes and their mechanisms.

Graphical abstract: Furo[3,2-c]coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms

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Article information


Submitted
11 Aug 2020
Accepted
01 Sep 2020
First published
10 Sep 2020

This article is Open Access

RSC Adv., 2020,10, 33344-33377
Article type
Review Article

Furo[3,2-c]coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms

I. Cortés, L. J. Cala, A. B. J. Bracca and T. S. Kaufman, RSC Adv., 2020, 10, 33344
DOI: 10.1039/D0RA06930B

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