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Issue 3, 2020
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SGLT inhibitors as antidiabetic agents: a comprehensive review

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Abstract

Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review, we cover the scientific studies on sodium/glucose cotransporter (SGLT) inhibitors published during the last decade. Our focus on providing an exhaustive overview of SGLT inhibitors enabled us to present their chemical classification for the first time.

Graphical abstract: SGLT inhibitors as antidiabetic agents: a comprehensive review

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Article information


Submitted
23 Oct 2019
Accepted
18 Dec 2019
First published
09 Jan 2020

This article is Open Access

RSC Adv., 2020,10, 1733-1756
Article type
Review Article

SGLT inhibitors as antidiabetic agents: a comprehensive review

R. P. Kshirsagar, A. A. Kulkarni, R. S. Chouthe, S. K. Pathan, H. D. Une, G. B. Reddy, P. V. Diwan, S. A. Ansari and J. N. Sangshetti, RSC Adv., 2020, 10, 1733
DOI: 10.1039/C9RA08706K

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