Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 19, 2013
Previous Article Next Article

Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette

Author affiliations

Abstract

Nanofluidic structures share many properties with ligand-gated ion channels. However, actuating ion conductance in artificial systems is a challenge. We have designed a system that uses a carbohydrate-responsive polymer to modulate ion conductance in a quartz nanopipette. The cationic polymer, a poly(vinylpyridine) quaternized with benzylboronic acid groups, undergoes a transition from swollen to collapsed upon binding to monosaccharides. As a result, the current rectification in nanopipettes can be reversibly switched depending on the concentration of monosaccharides. Such molecular actuation of nanofluidic conductance may be used in novel sensors and drug delivery systems.

Graphical abstract: Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette

Back to tab navigation

Supplementary files

Article information


Submitted
27 Apr 2013
Accepted
29 Jul 2013
First published
02 Aug 2013

Nanoscale, 2013,5, 9214-9221
Article type
Paper

Carbohydrate-actuated nanofluidic diode: switchable current rectification in a nanopipette

B. Vilozny, A. L. Wollenberg, P. Actis, D. Hwang, B. Singaram and N. Pourmand, Nanoscale, 2013, 5, 9214
DOI: 10.1039/C3NR02105J

Social activity

Search articles by author

Spotlight

Advertisements