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Issue 2, 2016
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Evaluation of toxicity of nanoclays and graphene oxide in vivo: a Paramecium caudatum study

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Abstract

We report here the successful use of a protozoan model organism P. caudatum to investigate the toxicity of clay nanoparticles (montmorillonite, halloysite, kaolin, and bentonite), silica nanospheres and graphene oxide nanoflakes. The distribution of nanoparticles inside the cells was investigated using enhanced dark-field microscopy. Biochemical and behavioural tests were employed to study the viability, vitality, nutrition and oxidative stress induction in ciliate protozoans. The nanoclay particles studied here exhibited very low or no toxicity towards P. caudatum, whereas graphene oxide was toxic.

Graphical abstract: Evaluation of toxicity of nanoclays and graphene oxide in vivo: a Paramecium caudatum study

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Publication details

The article was received on 16 Sep 2015, accepted on 13 Jan 2016 and first published on 14 Jan 2016


Article type: Paper
DOI: 10.1039/C5EN00201J
Environ. Sci.: Nano, 2016,3, 442-452
  • Open access: Creative Commons BY license
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    Evaluation of toxicity of nanoclays and graphene oxide in vivo: a Paramecium caudatum study

    M. Kryuchkova, A. Danilushkina, Y. Lvov and R. Fakhrullin, Environ. Sci.: Nano, 2016, 3, 442
    DOI: 10.1039/C5EN00201J

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