Issue 83, 2016

Boronate based fluorescence (ESIPT) probe for peroxynitrite

Abstract

A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester “protecting” unit. The “protecting” unit of the probe is removed by peroxynitrite to “turn-on” ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off–on response towards peroxynitrite, in HeLa and RAW 264.7 cells.

Graphical abstract: Boronate based fluorescence (ESIPT) probe for peroxynitrite

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
19 Aug 2016
Accepted
19 Sep 2016
First published
19 Sep 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 12350-12352

Boronate based fluorescence (ESIPT) probe for peroxynitrite

A. C. Sedgwick, X. Sun, G. Kim, J. Yoon, S. D. Bull and T. D. James, Chem. Commun., 2016, 52, 12350 DOI: 10.1039/C6CC06829D

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