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Issue 83, 2016
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Boronate based fluorescence (ESIPT) probe for peroxynitrite

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Abstract

A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester “protecting” unit. The “protecting” unit of the probe is removed by peroxynitrite to “turn-on” ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off–on response towards peroxynitrite, in HeLa and RAW 264.7 cells.

Graphical abstract: Boronate based fluorescence (ESIPT) probe for peroxynitrite

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Publication details

The article was received on 19 Aug 2016, accepted on 19 Sep 2016 and first published on 19 Sep 2016


Article type: Communication
DOI: 10.1039/C6CC06829D
Chem. Commun., 2016,52, 12350-12352
  • Open access: Creative Commons BY license
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    Boronate based fluorescence (ESIPT) probe for peroxynitrite

    A. C. Sedgwick, X. Sun, G. Kim, J. Yoon, S. D. Bull and T. D. James, Chem. Commun., 2016, 52, 12350
    DOI: 10.1039/C6CC06829D

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