Replicable 2.5D PDMS microfluidics with precision nanoscale features expand the dimensions of pore-scale flow studies

Abstract

Customizable 2.5D microfluidic chips, tailored for rock-on-a-chip studies, are developed using direct laser writing (DLW) and soft lithography. Chip microchannels feature varied cross-sectional shape and height, convergences as small as 1–2 µm, and controlled nanoscale surface roughness. The impact of these 2.5D features on pore-scale transport phenomena is demonstrated with trapped bubble dissolution experiments.

Graphical abstract: Replicable 2.5D PDMS microfluidics with precision nanoscale features expand the dimensions of pore-scale flow studies

Supplementary files

Article information

Article type
Communication
Submitted
01 Oct 2025
Accepted
10 Feb 2026
First published
16 Feb 2026
This article is Open Access
Creative Commons BY license

Soft Matter, 2026, Advance Article

Replicable 2.5D PDMS microfluidics with precision nanoscale features expand the dimensions of pore-scale flow studies

K. Yao and S. Kelly, Soft Matter, 2026, Advance Article , DOI: 10.1039/D5SM01004G

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