Issue 7, 2026, Issue in Progress

Graphene oxide functionalized tannic acid–trimethylolpropane triglycidyl ether nanoparticles: a versatile network nanocatalyst for synthesis of 4-substituted-1,5-benzodiazepine derivatives

Abstract

This work is described through a one-pot three-component reaction of o-phenylenediamine, and dimedone, under reflux conditions in aqueous ethanol/H2O (1 : 1 v/v, 5 mL) in the presence of GO@tannic acid–TTE. The main advantages of this method are the ease of operation, purification, and the absence of hazardous and expensive solvents and catalysts. Also, this catalyst has the ability to perform this reaction in large quantities on an industrial scale. FT-IR, TGA, XRD, EDX, elemental mapping, TEM, and SEM methods have been used to characterize the prepared nanocatalyst. The catalyst can be reused several times.

Graphical abstract: Graphene oxide functionalized tannic acid–trimethylolpropane triglycidyl ether nanoparticles: a versatile network nanocatalyst for synthesis of 4-substituted-1,5-benzodiazepine derivatives

Supplementary files

Article information

Article type
Paper
Submitted
08 Nov 2025
Accepted
04 Jan 2026
First published
28 Jan 2026
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2026,16, 5979-5989

Graphene oxide functionalized tannic acid–trimethylolpropane triglycidyl ether nanoparticles: a versatile network nanocatalyst for synthesis of 4-substituted-1,5-benzodiazepine derivatives

A. Gharehkhani, M. Hajjami and R. Hazbavi, RSC Adv., 2026, 16, 5979 DOI: 10.1039/D5RA08633G

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