Pd@CN-COF: A Pool for Palladium(0)-Catalyzed Reactions

Abstract

A new cyano-substituted olefin-linked COF was synthesized and utilized as a support for palladium nanoparticles. The resulting Pd@CN-COF was demonstrated as a versatile heterogeneous catalyst in cross-coupling reactions, cyanation, and allylic substitution with the productivity exceeding the commercial homogeneous precatalyst [Pd(PPh3)4]. The catalytic activity of Pd@CN-COF was further evaluated in synthetically valuable transformations towards industrially, agrochemically, and pharmacologically relevant products.