Tunable Electrosynthesis of Functionalized Phenoxazines from Alcohols and P₄S₁₀.

Abstract

A green and efficient electrochemical strategy has been developed for the three-component reaction of phenoxazine, alcohols and P₄S₁₀ under ambient conditions. Using inexpensive P₄S₁₀ as both the sulfur and phosphorus source, this method enables the synthesis of various phosphorodithiolated phenoxazines in moderate to good yields without external oxidants. Notably, the bis-phosphorodithiolation product can be readily obtained by adjusting the reaction time. Control experiments and radical trapping studies confirm that the reaction proceeds through a radical-mediated mechanism.