Visible-light induced sustainable photochemical approach for the synthesis of spirocyclic compounds

Abstract

The application of photocatalysis in organic synthesis has become essential because it enables mild, eco-friendly, and effective transformations to access essential molecular scaffolds. A sustainable and effective technique for generating spirocyclic compounds using photocatalysts is carried out via visible light-induced photochemical methods. This method enables the formation of intricate spirocyclic structures using easily accessible starting materials under moderate, eco-friendly conditions. Several visible light mediated spirocyclization reactions proceed via radical intermediates through a variety of processes, such as hydrogen atom transfer and single-electron transfer. The current developments in photocatalysed synthesis of spirocyclic compounds have been highlighted.

Graphical abstract: Visible-light induced sustainable photochemical approach for the synthesis of spirocyclic compounds

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Article information

Article type
Review Article
Submitted
21 Oct 2025
Accepted
07 Jan 2026
First published
07 Jan 2026

Org. Biomol. Chem., 2026, Advance Article

Visible-light induced sustainable photochemical approach for the synthesis of spirocyclic compounds

P. P. Singh, S. Sinha, P. Singh and V. Srivastava, Org. Biomol. Chem., 2026, Advance Article , DOI: 10.1039/D5OB01654A

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