Clinical Transformation of Afterglow Luminescence Imaging in Precision Surgery of Tumors: Opportunities and Challenges

Abstract

The afterglow luminescence imaging technology, as an emerging tool for precise tumor diagnosis and treatment, is providing intraoperative navigation and postoperative monitoring methods for surgeons. From a clinical perspective, this article systematically reviews the current application status, clinical transformation opportunities, and challenges of afterglow luminescent materials in tumor resection surgeries. From the perspective of a surgeon, it emphasized the future development needs and called for the establishment of a cross-disciplinary collaboration platform to jointly promote the application of the afterglow luminescence imaging from the laboratory to the clinic.

Article information

Article type
Minireview
Submitted
19 Dec 2025
Accepted
21 Feb 2026
First published
06 Mar 2026
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2026, Accepted Manuscript

Clinical Transformation of Afterglow Luminescence Imaging in Precision Surgery of Tumors: Opportunities and Challenges

J. Li, L. Ding, W. Ma, Y. He, Q. Li, Y. Yuan and Z. Li, Nanoscale, 2026, Accepted Manuscript , DOI: 10.1039/D5NR05374A

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