A visible light-promoted C-H insertion between diazoamides and 1,3-diketones leads to the corresponding 3-substituted-2-oxindoles in good yield. A subsequent reaction of the resulting product with hydrazine hydrate, followed by alkylation, provided biologically active 3-pyrazol-4-yl-indole derivatives in good to excellent yield, which can be easily scaled up to gram scale.
S. Muthusamy and S. Hariharan, New J. Chem., 2026, Accepted Manuscript , DOI: 10.1039/D5NJ04942C
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