The fluorescent properties of DNA/AgNCs are largely governed by the composition of AgNCs, nucleobase sequence, and the secondary structure of the DNA template. Here, by systematic incorporation of xeno-nucleic acid modifications, we demonstrate the potential of altering sugar chemistry of the template DNA backbone, as a novel factor in AgNC fluorescence modulation.
H. C. Yadavalli, R. Nagda, J. Kang, M. Cho, C. Lou, S. W. Yang, P. W. W. Thulstrup, M. J. Bjerrum and P. Shah, Nanoscale Adv., 2026, Accepted Manuscript , DOI: 10.1039/D5NA00862J
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