A sunlight-compatible photochemical thiol-ene reaction promoted by paracyclophane-derived photocatalyst

Abstract

A sustainable thiol-ene (yne) click reaction has been developed using paracyclophane derived photocatalyst (1-2.5 mol%) in ethanol under @LED405 or sunlight at room temperature. This methodology features simple conditions, broad scope and tolerates different functional groups either on olefin or thiol. Experimental probes demonstrate the radical character of the reaction and the quantum yield measurements suggest a close catalytic radical cycle over a chain mechanism.