Advances in the preparation, characterization and biological activity of food-borne selenium-enriched peptides

Abstract

As a vital trace nutrient for the human body, selenium is essential for many physiological functions. However, the prevalence of selenium insufficiency and associated conditions (such as osteoarthritis and Keshan disease) is increasing as a result of dietary habits and environmental variables. Because of its high bioavailability, low toxicity, and variety of biological activities, organic selenium-represented by bioactive selenium peptides-displays notable benefits in the field of nutritional supplements when compared to inorganic selenium compounds. The creation of foodderived selenium-enriched peptides has become a crucial area of functional food research as nutritional intervention concepts have advanced. The biological activity, structural characterization techniques, and optimization strategies for producing selenium-enriched peptides from dietary sources are all thoroughly reviewed in this study. The goal is to offer a theoretical foundation and technological references for the development of functional meals based on selenium peptides by incorporating the results of current research.

Article information

Article type
Review Article
Submitted
10 Nov 2025
Accepted
25 Feb 2026
First published
26 Feb 2026

Food Funct., 2026, Accepted Manuscript

Advances in the preparation, characterization and biological activity of food-borne selenium-enriched peptides

Y. Qiu, Z. Zhao, M. Wang and Y. Zhang, Food Funct., 2026, Accepted Manuscript , DOI: 10.1039/D5FO04850H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements