Effects of infant formula supplied with medium- and long-chain triacylglycerols and sn-2 palmitate on fecal lipid metabolome and microbiota profiles in healthy term infants: a parallel-controlled study

Abstract

Infant formula fortified with medium- and long-chain triacylglycerols and sn-2 palmitate showed a comparable fecal lipidomics pattern to breast milk. Significant correlations were observed between fecal lipid and beneficial microbiota such as Bifidobacterium. The results indicated that structured lipids influenced lipid metabolism and infant gut health.

Graphical abstract: Effects of infant formula supplied with medium- and long-chain triacylglycerols and sn-2 palmitate on fecal lipid metabolome and microbiota profiles in healthy term infants: a parallel-controlled study

Supplementary files

Article information

Article type
Communication
Submitted
04 Nov 2025
Accepted
09 Mar 2026
First published
24 Mar 2026

Food Funct., 2026, Advance Article

Effects of infant formula supplied with medium- and long-chain triacylglycerols and sn-2 palmitate on fecal lipid metabolome and microbiota profiles in healthy term infants: a parallel-controlled study

J. Yu, Z. Liu, M. Yang, Q. Bi, X. Zhou, Y. Qiu, X. Ye, W. Wei and X. Wang, Food Funct., 2026, Advance Article , DOI: 10.1039/D5FO04757A

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