Combined Operando UV/Vis and NMR spectroscopy gives Mechanistic Insight into the Reaction of Guaiazulene with 2,4-Dinitrobenzaldehyde

Abstract

In this proof-of-principle study, we apply combined NMR and UV/Vis spectroscopy to operando reaction monitoring of a 'classical' organic reaction. We show that identical intensity-vs.time courses are obtained for an intermediate visible in both NMR and UV/Vis, and propose a mechanism accounting for the dependence of the reaction on c(HPF6).

Supplementary files

Article information

Article type
Communication
Submitted
04 Dec 2025
Accepted
21 Apr 2026
First published
22 Apr 2026

Phys. Chem. Chem. Phys., 2026, Accepted Manuscript

Combined Operando UV/Vis and NMR spectroscopy gives Mechanistic Insight into the Reaction of Guaiazulene with 2,4-Dinitrobenzaldehyde

C. M. Thiele and K. Heckenberger, Phys. Chem. Chem. Phys., 2026, Accepted Manuscript , DOI: 10.1039/D5CP04718H

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