From the journal:

Chemical Communications

A highly selective near-infrared fluorescent probe for imaging peroxynitrite in the brains of epileptic mice

Yuqing Hu,   Qiu-Lian Hao,   Xiaohang Wang,   Xin-Rong Li,   Zixuan Xu,   Lu-Lu Sun,   Tianlin Ni,   Xianzhi Chai,   Hai-Hao Han  and  Junji Zhang  

Abstract

A ratiometric near-infrared probe CCy7-DP was developed for peroxynitrite detection, utilizing a highly selective additionelimination reaction between ONOO -and diphenyl phosphinate. This reaction triggered an electron rearrangement of the cyanine skeleton and a blue shift in fluorescence, enabling high-contrast imaging of peroxynitrite in the brains of epileptic mice.

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Article information

DOI
https://doi.org/10.1039/D6CC02864K
Article type
Communication
Submitted
09 May 2026
Accepted
13 Jun 2026
First published
16 Jun 2026

Chem. Commun., 2026, Accepted Manuscript

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A highly selective near-infrared fluorescent probe for imaging peroxynitrite in the brains of epileptic mice

Y. Hu, Q. Hao, X. Wang, X. Li, Z. Xu, L. Sun, T. Ni, X. Chai, H. Han and J. Zhang, Chem. Commun., 2026, Accepted Manuscript , DOI: 10.1039/D6CC02864K

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