A One-Step Immunoassay of Tau Protein Based on Flow Cytometric Counting of Target-Induced Nanoaggregates

Abstract

A rapid one-step flow cytometry immunoassay is developed by counting the number of target protein-induced nanoaggregates. Without any separation or washing steps, it quantifies Tau protein rapidly with a lowest detectable concentration of 5 pg mL⁻¹ in a mix-and-read manner.

Supplementary files

Article information

Article type
Communication
Submitted
13 Apr 2026
Accepted
24 Jun 2026
First published
24 Jun 2026

Chem. Commun., 2026, Accepted Manuscript

A One-Step Immunoassay of Tau Protein Based on Flow Cytometric Counting of Target-Induced Nanoaggregates

J. Sun, Y. Qi, J. Zhang, W. Ren and C. Liu, Chem. Commun., 2026, Accepted Manuscript , DOI: 10.1039/D6CC02268E

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