Chiral Supramolecular Alloys: Programmable 2D–3D Control via Co-assembly of Isomorphous β-Peptide Foldamers

Abstract

We report the co-assembly of isomorphous yet chemically distinct β-peptide foldamers, creating chiral supramolecular alloys. This system enables composition-dependent 2D–3D control, programmably steering the morphology from 3D molar-tooth to 2D square-plate architectures. This alloy-like blending principle provides a general strategy for the programmable design of foldamer-based supramolecular systems.