Acyclic cucurbituril as sequestrant for acetaminophen

Abstract

Acyclic CB[n]-type host H4 functions as a solid state sequestrant for pharmaceutical micropollutants (PMs) from water, reaching up to 99.8% removal efficiency for acetaminophen within 5 minutes. A head-to-head study shows H4 performs at least as well as activated charcoal (DARCO®) at sequestering acetaminophen from simulated gastric fluid.

Graphical abstract: Acyclic cucurbituril as sequestrant for acetaminophen

Supplementary files

Article information

Article type
Communication
Submitted
27 Mar 2026
Accepted
12 May 2026
First published
21 May 2026
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2026, Advance Article

Acyclic cucurbituril as sequestrant for acetaminophen

J. S. Mogensen, T. M. Hofmann, S. Perera, Y. Lie, M. Pittelkow and L. Isaacs, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D6CC01879C

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