Cross-coupling of aryl aldehydes and benzyl chlorides enabled by dual N-heterocyclic carbene/cobalt catalysis

Abstract

We have developed a dual N-heterocyclic carbene/cobalt-salen catalytic system for the cross-coupling between aryl aldehydes and benzyl chlorides via direct C-H activation of aldehydes. The catalysts employed are readily accessible and the transformation affords ketones in moderate to high yields.

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Article information

Article type
Communication
Submitted
26 Feb 2026
Accepted
20 Apr 2026
First published
21 Apr 2026
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2026, Accepted Manuscript

Cross-coupling of aryl aldehydes and benzyl chlorides enabled by dual N-heterocyclic carbene/cobalt catalysis

H. Jomaa, D. Martin and E. Tomás-Mendivil, Chem. Commun., 2026, Accepted Manuscript , DOI: 10.1039/D6CC01204C

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