A palladium-catalyzed direct carbonylative amidation that enables the efficient coupling of benzylic alcohols with alkylamines under mild conditions has been developed. Key to the success is the use of pentafluoropyridine as an activating group, which facilitates selective alcohol activation and suppresses undesired side reactions.
To support increased transparency, we offer authors the option to publish the peer review history alongside their article.
Z. Yin, H. Li, X. Qin, M. Liu, C. Wang and X. Wu, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D6CC01058J
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...
