Recent Advancements on Carbonylative Synthesis of Quinolinones

Abstract

Carbonylation reactions, which rely on the controlled incorporation of carbon monoxide into organic substrates, represent a key tool in both organic and industrial chemistry. Carbonylation offers an efficient route to carbonyl-containing compounds starting from simple and readily available substrates, and it remains a highly active area of research in organometallic chemistry and catalysis. Current efforts focus on developing new catalysts, more efficient and sustainable methodologies, and innovative applications in emerging areas such as green chemistry and asymmetric synthesis. Given the great importance of heterocyclic compounds, the carbonylative approach has become increasingly important for their synthesis. In this review, as a class of benzo-fused nitrogen-containing heterocyclic compounds, we summarize and discuss the achievements on the synthesis of quinolinone derivatives via carbonylative approaches.