Regio- and diastereoselective synthesis of multi-substituted silacyclopentanes by catalytic cyclosilylborylation of styryl(vinyl)silanes

Abstract

A NaOtBu-catalyzed regio- and diastereoselective cyclosilylborylation of styryl(vinyl)silanes with silylboronates has been developed for the synthesis of multi-substituted silacyclopentanes. 2-Silyl-5-boryl-1-silacyclopentanes obtained in the present catalysis can be further functionalized by taking advantage of the reactivity of the silyl and boryl groups.