Alternating current polarity for electrochemical de novo synthesis of 3,3′-bisoxindoles

Abstract

A radical-involved cascade reaction provides straightforward and efficient access to structurally complex building blocks from readily available substrates. Herein, we report an unprecedented electrochemical synthesis of 3,3′-bisoxindoles through three newly formed C–C bonds enabled by alternating current polarity, which obviates the need for external oxidants and showcases excellent chemoselectivity.