Photoredox mediated synthesis of propargylic sulfoxides: a one-step aerobic approach

Abstract

We report the first photoredox-mediated one-step synthesis of propargylic sulfoxides from (3-chloroprop-1-yn-1-yl)benzene and thiols. The protocol obviates the need for external oxidants typically required for the oxidation of sulfides to sulfoxides. The approach offers a streamlined platform for accessing these valuable organosulfur compounds in a single step, with high chemoselectivity and functional-group tolerance.