The anion–π+ interaction strategy enhances the PDT antibacterial performance of AIE-active photosensitizers

Ying Zhang; Renmanduhu Sha; Jianye Gong; Lingxiu Liu; Lina Feng; Weijing Zhang; Guoyu Jiang; Jianguo Wang

doi:10.1039/D5CC07430D

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The anion–π⁺ interaction strategy enhances the PDT antibacterial performance of AIE-active photosensitizers

Ying Zhang,^a Renmanduhu Sha,^a Jianye Gong,^a Lingxiu Liu,^a Lina Feng,^a Weijing Zhang,^b Guoyu Jiang

*^a and Jianguo Wang

*^a

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* Corresponding authors

^a College of Chemistry and Chemical Engineering, Institute of Green Chemistry and Environment, Institutes of Biomedical Sciences, Inner Mongolia Key Laboratory of Synthesis and Application of Organic Functional Molecules, Inner Mongolia University, Hohhot 010021, P. R. China
E-mail: jiangguoyu@mail.ipc.ac.cn, wangjg@iccas.ac.cn

^b Xi’an Modern Chemistry Research Institute, Xi’an 710069, P. R. China

Abstract

Leveraging anion–π⁺ interactions, the near-infrared photosensitizer DTPAP-2B integrates efficient ROS generation with high bacterial affinity for superior photodynamic antibacterial performance.

This article is part of the themed collection: Aggregation-Induced Emission

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DOI: https://doi.org/10.1039/D5CC07430D
Article type: Communication
Submitted: 31 Dec 2025
Accepted: 12 Feb 2026
First published: 13 Feb 2026

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Chem. Commun., 2026, Advance Article

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The anion–π⁺ interaction strategy enhances the PDT antibacterial performance of AIE-active photosensitizers

Y. Zhang, R. Sha, J. Gong, L. Liu, L. Feng, W. Zhang, G. Jiang and J. Wang, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D5CC07430D

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The anion–π⁺ interaction strategy enhances the PDT antibacterial performance of AIE-active photosensitizers

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The anion–π⁺ interaction strategy enhances the PDT antibacterial performance of AIE-active photosensitizers

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