Differential self-assembly of sequence-isomeric phosphoestamers

Abstract

Phosphoestamers self-assemble into an array of superstructures according to their sequence and thus provide a useful model for understanding sequence/structure relationships. To explore this, we synthesised all tetrameric phosphoestamers composed of equal ratios of C12 and HEG monomers and examined their self-assemblies in a combined experimental/computational workflow.