Construction of bright color-tunable chemiluminescent nanodots and their applications for in vivo bioimaging

Abstract

A general strategy was proposed to construct a series of highly bright color-tunable chemiluminescent nanodots. The near-infrared chemiluminescence nanodots achieved high-contrast chemiluminescence imaging with a signal-to-noise ratio exceeding 200 through 5 mm of muscle tissue, a maximum penetration depth of approximately 2.4 cm, and demonstrated great potential for in vivo bioimaging.