Minimal-tag polyamines for in situ probing of their intracellular distribution
Abstract
Propargyl polyamines (putrescine, spermidine, and spermine) were synthesized and evaluated as minimal-tag analogs for high-resolution intracellular imaging in mammalian cells and zebrafish. These compounds showed structure-dependent differences in subcellular distribution with unprecedented resolution, discriminating among closely related polyamines.

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