Highly stable self-assembled nanotubes from a bipyridinium-based amphiphilic pseudopeptide

Abstract

Herein, we report an amphiphilic pseudopeptide that spontaneously self-assembles into monodisperse cationic nanotubes under physiological conditions. These nanotubes exhibit fast self-assembly, remarkable thermal stability and thermoreversibility. The self-assembly concentration range is exceptionally broad, enabling the formation of stable hydrogels at concentrations above 5 mM while preserving the nanostructure at micromolar levels.