From the journal:

Chemical Communications

A DNAzyme-induced disposable strip biosensor for visual detection of trace levels of UO22+ in remote areas

Ying Zeng,a   Yimei Guo,a   Xu Cui,a   Xiaoya Ren,a   Jiafeng Pan ORCID logo *a  and  Fei Yang ORCID logo *a  

* Corresponding authors

a Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China
E-mail: jiafengpan0928@163.com, yangfeilong@126.com

Abstract

A strip biosensor was constructed for UO22+ detection based on DNAzyme-mediated cleavage and AuNP aggregation, achieving a low detection limit of 160 pM. With a visual mode, high sensitivity, and excellent specificity, our sensor enables on-site detection of UO22+ in remote areas.

Graphical abstract: A DNAzyme-induced disposable strip biosensor for visual detection of trace levels of UO22+ in remote areas

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Article information

DOI
https://doi.org/10.1039/D5CC05899F
Article type
Communication
Submitted
16 Oct 2025
Accepted
09 Dec 2025
First published
09 Dec 2025

Chem. Commun., 2026, Advance Article

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A DNAzyme-induced disposable strip biosensor for visual detection of trace levels of UO22+ in remote areas

Y. Zeng, Y. Guo, X. Cui, X. Ren, J. Pan and F. Yang, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D5CC05899F

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