PolyA-Tail-Mediated Assembly of a Gold Nanoparticle-Based Turn-on Fluorescent Aptasensor for Ultrasensitive Detection of Perfluorooctanoic acid

Abstract

A turn-on fluorescent aptasensor for PFOA is developed using a polyA-tailed aptamer anchored on gold nanoparticles and a fluorescently labeled cDNA. The displacement of cDNA by PFOA restores fluorescence, enabling ultrasensitive detection with a 1.3 nmol L-1 limit, demonstrated by satisfactory recovery in spiked fish samples.

Supplementary files

Article information

Article type
Communication
Submitted
08 Feb 2026
Accepted
03 May 2026
First published
05 May 2026

Anal. Methods, 2026, Accepted Manuscript

PolyA-Tail-Mediated Assembly of a Gold Nanoparticle-Based Turn-on Fluorescent Aptasensor for Ultrasensitive Detection of Perfluorooctanoic acid

Z. Li, L. Yan, X. Zhao, H. Lin, L. Chen and X. Yan, Anal. Methods, 2026, Accepted Manuscript , DOI: 10.1039/D6AY00236F

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