Magnetic Chitosan/ZIF-L/KCDs Granular-Leaf Hybrid Nanocomposite for Magnetic Dispersive µSolid Phase Extraction of mycotoxins from Ziziphus Jujuba, Nuts and Grains

Abstract

In this study, a novel magnetic chitosan/zeolitic imidazolate frameworks-L /kiwi peel-derived carbon dots (MCS/ZIF-L/KCDs) granular-leaf hybrid nanocomposite was synthesized and used for magnetic dispersive µ solid-phase extraction (MD-µSPE) of aflatoxins B1, B2, G1, and G2, and the extracts were analyzed by high-performance liquid chromatography with fluorescence detection (HPLC-FLD). The sorbent was characterized using Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. The influential parameters were optimized, and under optimum conditions, the developed method showed excellent analytical performance with limits of detection (LOD) of 0.002–0.003 µg kg-1, limits of quantification (LOQ) of 0.007–0.009 µg kg-1, and linear dynamic ranges (LDR) of 0.01–750 and 0.01–1000 µg kg-1, depending on the analyte and matrix. The relative recoveries (%) of 91.0-99.4, the intra-day (n=6) and inter-day (5 days, n=3) precisions at ≤3.5 % and ≤3.0 %, were acquired, respectively, which confirmed satisfactory capability, reproducibility, and repeatability. The proposed method presented good compliance with green analytical chemistry rules.