Simultaneous electrochemical detection of dopamine and paracetamol using a modified electrode with hydrothermal treatment of neodymium oxide and carbon paste

Abstract

In this report, the modification of the carbon-based electrode with neodymium oxide after hydrothermal treatment led to a significant increase in the electroactive and conductive properties of the electrode. The results revealed that the particle size of the neodymium oxide and carbon paste mixture after HT was more uniform and smaller, ranging from 2000 to 10000 nm in size to 600 to 900 nm in size. This change increased the electroactive activity of the simultaneous anodic current of dopamine and paracetamol by more than 100% compared with that of the neodymium oxide and carbon paste mixture that did not undergo hydrothermal treatment. The electroanalytical application of this new composite allowed the simultaneous detection of dopamine and paracetamol. The optimum pH value and variables such as accumulation potential, accumulation time, frequency and amplitude were 3.5, 0.0 V, 30s, 5 Hz and 0.05 V with detection limits of 0.06 and 0.02 µmol/L, respectively. and its application in real samples such as cold syrup for paracetamol and human urine sample for dopamine