A reflection on frustrated Lewis pairs 20 years on: the gift that keeps on giving

Abstract

This commentary reflects on the remarkably broad impact the concept of “frustrated Lewis pairs” (FLPs) has had over the past 20 years. Since its initial articulation, this concept has found applications across the periodic table and the discipline, leading to new avenues for synthesis and catalysis, building on the 2011 publication (R. C. Neu, E. Otten, A. Lough and D. W. Stephan, Chem. Sci., 2011, 2, 170, https://doi.org/10.1039/C0SC00398K).

Graphical abstract: A reflection on frustrated Lewis pairs 20 years on: the gift that keeps on giving

Article information

Article type
Commentary
First published
24 Sep 2025
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2025, Advance Article

A reflection on frustrated Lewis pairs 20 years on: the gift that keeps on giving

R. L. Melen and D. W. Stephan, Chem. Sci., 2025, Advance Article , DOI: 10.1039/D5SC90195B

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